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…due to severe inclement weather, Dr. Heng (Danny - then a Medical Oncology resident) was unable to go Boxing Day shopping with his family in December 2006. Instead, he pulled out his laptop and got to work. He began by collecting data on patients with metastatic RCC treated with targeted therapy from Vancouver (British Columbia Cancer Agency). These initial 69 patients were the first group to enter what is now the IMDC. At the same time, Dr. Choueiri (Toni) was data gathering at Cleveland Clinic prior to moving to Boston, where he incorporated additional patients from Harvard-affiliated sites, including the Dana-Farber Cancer Institute and Beth Israel Deaconess Medical Center.

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